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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-4
All Species:
13.03
Human Site:
T307
Identified Species:
23.89
UniProt:
Q9H2Z4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2Z4
NP_149416.1
354
36179
T307
G
P
Q
P
P
A
P
T
P
A
P
E
L
E
E
Chimpanzee
Pan troglodytes
XP_525278
419
42955
T372
G
P
Q
P
P
A
P
T
P
A
P
E
L
E
E
Rhesus Macaque
Macaca mulatta
XP_001093634
451
46942
T404
G
P
Q
P
P
A
P
T
P
A
P
E
L
E
E
Dog
Lupus familis
XP_849082
233
24205
E193
T
P
A
P
E
L
E
E
L
S
P
S
P
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQM3
354
36207
T307
G
Q
Q
P
Q
A
P
T
P
A
P
E
L
E
E
Rat
Rattus norvegicus
P23441
372
38536
G326
G
H
Q
P
G
S
A
G
Q
S
P
D
L
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90788
294
33054
V254
S
Y
P
A
V
Q
P
V
Q
P
S
A
A
G
N
Frog
Xenopus laevis
P42587
196
22791
C156
L
V
R
D
G
K
P
C
H
T
L
K
A
Q
D
Zebra Danio
Brachydanio rerio
Q90481
269
30288
P229
A
T
F
Q
A
G
I
P
F
S
A
Y
S
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22808
723
76404
A672
T
A
T
A
M
Q
N
A
A
A
H
H
L
V
A
Honey Bee
Apis mellifera
XP_394578
395
41030
L321
R
G
G
P
S
A
A
L
A
S
P
A
P
H
M
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
P259
S
E
K
P
V
L
K
P
S
G
V
F
G
L
P
Sea Urchin
Strong. purpuratus
NP_999800
411
44821
M364
H
A
H
H
Q
H
P
M
S
Q
A
S
L
H
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.2
77.1
61.2
N.A.
94.3
59.4
N.A.
N.A.
29.9
28.8
31
N.A.
24.3
37.9
31.6
38.9
Protein Similarity:
100
84.2
77.1
62.9
N.A.
94.6
66.4
N.A.
N.A.
42
38.4
42.9
N.A.
32
49.6
43.7
51.3
P-Site Identity:
100
100
100
20
N.A.
86.6
33.3
N.A.
N.A.
6.6
6.6
0
N.A.
13.3
20
6.6
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
86.6
53.3
N.A.
N.A.
6.6
33.3
13.3
N.A.
13.3
26.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
16
8
39
16
8
16
39
16
16
16
16
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
8
% D
% Glu:
0
8
0
0
8
0
8
8
0
0
0
31
0
31
31
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
39
8
8
0
16
8
0
8
0
8
0
0
8
8
0
% G
% His:
8
8
8
8
0
8
0
0
8
0
8
8
0
16
16
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
8
8
0
0
0
0
8
0
0
0
% K
% Leu:
8
0
0
0
0
16
0
8
8
0
8
0
54
8
0
% L
% Met:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
31
8
62
24
0
54
16
31
8
54
0
16
8
8
% P
% Gln:
0
8
39
8
16
16
0
0
16
8
0
0
0
8
8
% Q
% Arg:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
0
0
8
8
0
0
16
31
8
16
8
0
0
% S
% Thr:
16
8
8
0
0
0
0
31
0
8
0
0
0
0
0
% T
% Val:
0
8
0
0
16
0
0
8
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _